Physica Medica: European Journal of Medical Physics
Volume 23, Issue 3 , Pages 115-125, December 2007

A free program for calculating EUD-based NTCP and TCP in external beam radiotherapy

  • Hiram A. Gay

      Affiliations

    • Department of Radiation Oncology, The Brody School of Medicine at East Carolina University, 600 Moye Boulevard, Greenville, NC 27834, USA
    • Corresponding Author InformationCorresponding author. Tel.: +1 252 744 2900.
    • ,
  • Andrzej Niemierko

      Affiliations

    • Department of Radiation Oncology, Massachusetts General Hospital, Boston, MA, USA

Received 18 July 2007; accepted 23 July 2007. published online 10 September 2007.

Abstract 

Purpose

Provide a simple research tool that may be used to calculate the NCTP or TCP of a particular treatment plan. Illustrate the implementation of the EUD-based NTCP and TCP models as a research tool.

Methods and materials

A high-level computing language was chosen to implement Niemierko's EUD-based NTCP and TCP mathematical models. The necessary treatment planning software requirements were clearly defined.

Results

The computer code is presented and explained. Six simple examples were created to quickly troubleshoot the reader's code implementation. A table of model parameters based on the Emami data was generated.

Keywords: Normal tissue complication probability, Tumor control probability, Equivalent uniform dose, Dose–volume histogram, EUD, NTCP, TCP, DVH, Software, Program, Radiotherapy, Radiation

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PII: S1120-1797(07)00060-9

doi:10.1016/j.ejmp.2007.07.001

Physica Medica: European Journal of Medical Physics
Volume 23, Issue 3 , Pages 115-125, December 2007

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