Physica Medica: European Journal of Medical Physics
Volume 26, Issue 1 , Pages 34-37, January 2010

The feasibility of computational modelling technique to detect the bladder cancer

  • Ahmad Keshtkar

      Affiliations

    • Medical Physics Department, Medical Faculty, Tabriz University of Medical Sciences, Tabriz, Iran
    • Corresponding Author InformationCorresponding author.
  • ,
  • Asghar Mesbahi

      Affiliations

    • Medical Physics Department, Medical Faculty, Tabriz University of Medical Sciences, Tabriz, Iran
  • ,
  • S.H. Rasta

      Affiliations

    • Medical Physics Department, Medical Faculty, Tabriz University of Medical Sciences, Tabriz, Iran
  • ,
  • Asghar Keshtkar

      Affiliations

    • The Faculty of Engineering and Technology, Imam Khomeini International University, Ghazvin, Iran

Received 1 November 2008; received in revised form 31 May 2009; accepted 17 June 2009. published online 15 July 2009.

Abstract 

A numerical technique, finite element analysis (FEA) was used to model the electrical properties, the bio impedance of the bladder tissue in order to predict the bladder cancer. This model results showed that the normal bladder tissue have significantly higher impedance than the malignant tissue that was in opposite with the impedance measurements or the experimental results. Therefore, this difference can be explained using the effects of inflammation, oedema on the urothelium and the property of the bladder as a distensible organ. Furthermore, the different current distributions inside the bladder tissue (in histological layers) in normal and malignant cases and finally different applied pressures over the bladder tissue can cause different impedances for the bladder tissue. Finally, it is believed that further studies have to be carried out to characterise the human bladder tissue using the electrical impedance measurement and modelling techniques.

Keywords: Numerical technique, Bio impedance, Normal and malignant bladder tissue

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PII: S1120-1797(09)00034-9

doi:10.1016/j.ejmp.2009.06.001

Physica Medica: European Journal of Medical Physics
Volume 26, Issue 1 , Pages 34-37, January 2010