Physica Medica: European Journal of Medical Physics
Volume 26, Issue 4 , Pages 177-183 , October 2010

Stochastic modelling of the role of cisplatin in altered fractionation schedules for head and neck cancer

  • Loredana Marcu

      Affiliations

    • University of Adelaide, School of Chemistry and Physics, Australia
    • University of Oradea, Faculty of Science, Romania
    • Corresponding Author InformationCorresponding author. University of Oradea, 1 Universitatii str, 410086 Oradea, Romania.
    • ,
  • Eva Bezak

      Affiliations

    • University of Adelaide, School of Chemistry and Physics, Australia
    • Royal Adelaide Hospital, Department of Medical Physics, Australia

Received 12 January 2009 ,Revised 12 October 2009 ,Accepted 20 November 2009.

References 

  1. Trott KR. Cell repopulation and overall treatment time. Int J Radiat Oncol Biol Phys. 1990;19:1071–1075
  2. Fu K, Pajak T, Trotti A, Jones CU, Spence SA, Phillips T, et al. Radiation Therapy Oncology Group (RTOG) phase III randomized study to compare hyperfractionation and two variants of accelerated fractionation to standard fractionation radiotherapy for head and neck squamous cell carcinomas: first report of RTOG 9003. Int J Radiat Oncol Biol Phys. 2000;48:7–16
  3. Jeremic B, Shibamoto Y, Stanisavljevic B, Milojevic L, Milicic B, Nikolic N, et al. Radiation therapy alone or with concurrent low-dose daily either cisplatin or carboplatin in locally advanced unresectable squamous cell carcinoma of the head and neck: a prospective randomized trial. Radiother Oncol. 1997;43:29–37
  4. Reed E, Kohn KW. Platinum analogues. In:  Chabner B,  Collins JM editor. Cancer chemotherapy-principles and practice. Philadelphia: Lippincott; 1990;
  5. Sorenson CM, Barry MA, Eastman A. Analysis of events associated with cell cycle arrest at G2 phase and cell death induced by cisplatin. J Natl Cancer Inst. 1990;82:749–754
  6. In:  Lippert B editors. Cisplatin – chemistry and biochemistry of a leading anticancer drug. Zürich: Wiley-VCH; 1999;
  7. Lawrence TS, Blackstock AW, McGinn C. The mechanism of action of radiosensitization of conventional chemotherapeutic agents. Semin Radiat Oncol. 2003;13:13–21
  8. Dewit L. Combined treatment of radiation and cis-diamminedichloroplatinum (II): a review of experimental and clinical data. Int J Radiat Oncol Biol Phys. 1987;13:403–426
  9. Nakamoto S, Mitsuhashi N, Takahashi T, Sakurai H, Niibe H. An interaction of cisplatin and radiation in two rat yolk sac tumour cell lines with different radiosensitivities in vitro. Int J Radiat Biol. 1996;70:747–753
  10. Marcu L, Bezak E, Olver I. Scheduling cisplatin and radiotherapy in the treatment of squamous cell carcinomas of the head and neck: a modelling approach. Phys Med Biol. 2006;51:3625–3637
  11. Marcu L, van Doorn T, Zavgorodni S, Olver I. Growth of a virtual tumour using probabilistic methods of cell generation. Australas Phys Eng Sci Med. 2002;25:155–161
  12. Begg AC. Cell proliferation in tumours. In:  Steel GG editors. Basic clinical radiobiology. 2nd ed. New York: Oxford University Press; 1997;p. 14–23
  13. Steel GG. The growth rate of tumours. In:  Steel GG editors. Basic clinical radiobiology. 2nd ed. New York: Oxford University Press; 1997;p. 8–13
  14. Tannock IF, Hill RP. The basic science of oncology. 2nd ed.. McGraw-Hill; 1992;pp. 155–176
  15. Hall E. Radiobiology for the radiologist. 5th ed.. Lippincott Williams & Wilkins; 2000;
  16. Tubiana M. The growth and progression of human tumours: implications for management strategy. Radiother Oncol. 1986;6:167–184
  17. Bourhis J, Overgaard J, Audry H, Ang K, Saunders M, Bernier J, et al. Hyperfractionated or accelerated radiotherapy in head and neck cancer: a meta-analysis. Lancet. 2006;368(9538):843–854
  18. Vivek R, Baludavid M, Mohanram R, Chitra , Amanullah , Vijayalakshmi , et al. Concurrent chemo-irradiation using accelerated concomitant boost radiation therapy in loco-regionally advanced head and neck squamous cell carcinomas. J Cancer Res Ther. 2006;2(3):90–96
  19. Beckmann GK, Hoppe F, Pfreundner L, Flentje MP. Hyperfractionated accelerated radiotherapy in combination with weekly cisplatin for locally advanced head and neck cancer. Head Neck. 2005;27(1):36–43
  20. Garden AS, Harris J, Trotti A, Jones CU, Carrascosa L, Cheng JD, et al. Long-term results of concomitant boost radiation plus concurrent cisplatin for advanced head and neck carcinomas: a phase II trial of the radiation therapy oncology group (RTOG 99-14). Int J Radiat Oncol Biol Phys. 2008;71(5):p. 1351–1355

PII: S1120-1797(09)00069-6

doi: 10.1016/j.ejmp.2009.11.004

Physica Medica: European Journal of Medical Physics
Volume 26, Issue 4 , Pages 177-183 , October 2010

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